Examination ScholarshipProgrammes
Admission 2025-26

Computational Biology & Biotechnology

About

The Department of Computational Biology and Biotechnology is an interdisciplinary academic unit within the university established 2023 which is dedicated to the study and advancement of computational methods and technologies in the field of biology and biotechnology. This department aims to bridge the gap between biology, computer science, mathematics, and engineering to develop new methods and tools for understanding and manipulating biological systems.

Courses and research opportunities in this department can cover a wide range of topics, including but not limited to:

  1. Bioinformatics: The use of computational tools to gather, store, analyze, and visualize biological data. This can include genomic data, proteomic data, metabolomic data, etc.
  2. Systems Biology: The computational and mathematical modeling of complex biological systems. This field aims to understand how the components of a biological system interact with each other to bring about the behavior of the system as a whole.
  3. Genomics and Proteomics: The study of genomes (the complete set of genes in an organism) and proteomes (the complete set of proteins expressed by a genome) using computational methods.
  4. Structural Biology: The use of computational methods to study the structure and function of biological macromolecules like proteins and nucleic acids.
  5. Biological Data Mining: The use of machine learning and statistical techniques to uncover patterns or associations in large datasets of biological information.
  6. Biotechnology: The application of computational methods in the development and improvement of products and technologies in areas such as agriculture, medicine, and industry. This could involve work in genetic engineering, synthetic biology, and more.

Faculty in such a department might come from diverse backgrounds, including biology, computer science, mathematics, and various fields of engineering. Their research could span a wide range of topics, from developing new algorithms for analyzing genomic data to creating computational models of biological systems to designing new biotechnologies.

Students graduating from this department could find opportunities in various fields such as academic research, pharmaceuticals, healthcare, agriculture, and bioinformatics, among others. They would be equipped with skills in data analysis, programming, machine learning, as well as a strong understanding of biological processes.

As the field of computational biology and biotechnology is rapidly evolving, the department would likely also be very forward-thinking and adaptive, continually updating its curriculum and research focus to stay at the forefront of this exciting intersection of biology, computation, and technology.

Courses & Programs

  • B.Sc. (Biotechnology) Four- Year Undergraduate Programme
  • M.Sc. in Biotechnology 
  • M.Sc. in Cancer Biology
  • M.Sc. in Bioinformatics
  • Integrated M.Sc. - Ph.D. in Cancer Biology
  • Integrated M.Sc. - Ph.D. in Bioinformatics
  • Ph.D.

Department Head

Dr. Kishore Sarma
Designation- HoD(i/c) & Assistant Professor

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People

Dr. Amal Ch. Kataki
Designation- Professor & Director, Health Education & Research

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Dr. Kishore Sarma
Designation- HoD(i/c) & Assistant Professor

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Dr. Kangkana Kataki
Designation- Assistant Professor

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Dr. Kaushik Kumar Bharadwaj
Designation- Assistant Professor

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Research & Publications

Conference and Seminar Publication

  1. Exploring the Antiovarian cancer efficacy of Arctium lappa using Computer Aided Drug Discovery and Machine Learning Approach, (2025), 2nd international conference on Data Driven AI, held at the Assam Kaziranga University, Jorhat, Assam, India.
  2. Fungal metabolites as anti-ovarian cancer leads: A computational discovery approach, (2025), National Conference on Bioresource research, Management and Susceptibility, B Borooah College, Guwahati, Assam, India
  3. Exploring plant-derived compounds from Northeast India for Ovarian cancer: A Machine learning and network pharmacological approach, (2025), International Seminar on Interdisciplinary Approaches for a Sustainable World, Chandra Nath Bezbaruah (CNB) College, Bokakhat in collaboration with Bodoland University, Kokrajhar, Assam, India.
  4. Targeting the Thiamine Biosynthesis Pathway in Leishmaniasis: Insights into in-silico prediction of Rheediaxanthone A as a Promising Drug Candidate, (2023), PHARMAGENESIS 2023, Rahman Institute of Pharmaceutical Sciences and Research, Guwahati, Assam, India.
  5. In silico investigation and library preparation of active compounds from Trigonella foenumgraecum (Fenugreek) as potent lead compound and future drug candidate against Alzheimer’s disease. (2023), PHARMAGENESIS 2023, Rahman Institute of Pharmaceutical Sciences and Research, Guwahati, Assam, India.

Journals

  1. Sarmah, K., Sarma, K., Borkakoty, B. et al. A Comprehensive Genomic Investigation of Mumps Virus Genotype G Isolates from Dibrugarh, Assam: Insights from Whole Genome Analysis. Indian J Microbiol (2025). https://doi.org/10.1007/s12088-025-01489-6
  2. Talukdar, J., Kataki, K., Choudhury, B.N., Baruah M.N., Bhattacharyya M., Sarma M.P, Bhattacharjee M, Das P.P, Kalita S, Medhi S. Downregulation of SMAD2 and SMAD4 is associated with poor prognosis and shorter survival in esophageal squamous cell carcinoma. Mol Biol Rep 52, 274 (2025). https://doi.org/10.1007/s11033-025-10390-w.
  3. Sarmah K, Sharma A, Sarma K, Alam ST, Dutta BS, Deka E, Laskar SA, Tishya NS, Lakshmi Priya MS, Baishya AC. Genomic analysis of Varicella zoster virus strains during an outbreak with atypical clinical presentations in Biswanath district of Assam, India. Virus Genes. 2025 Apr 12. doi: 10.1007/s11262-025-02156-0.
  4. Sarmah K, Sarma K, Borah PK, Sharma A, Mahanta J, Borkakoty B. Mumps in Patients with Acute Encephalitis Syndrome in Assam, India during January 2018 to July 2021. Indian J Public Health. 2025 Jan 1;69(1):107-110. doi: 10.4103/ijph.ijph_175_23. Epub 2025 Mar 21. PMID: 40214328.
  5. Queen Saikia, Kamal Adhikari, Airy Sanjeev, Ajit Hazarika, Kishore Sarma, Isoliquiritigenin: a potential drug candidate for the management of erectile dysfunction, Journal of Pharmacy and Pharmacology, Volume 76, Issue 8, August 2024, Pages 1065–1077, https://doi.org/10.1093/jpp/rgae054
  6. Das S, Medhi D, Talukdar AJ, Raja D, Sarma K, Sarma A, Saikia L. Hepatitis C virus genotypes among population with reported risk factors in Assam, north-east India: Emergence of genotype-8. Indian J Med Res. 2024 Jul;160(1):43-50. doi: 10.25259/ijmr_1222_23. PMID: 39382494; PMCID: PMC11463879.
  7. Talukdar J, Malik A, Kataki K, Choudhury BN, Baruah MN, Bhattacharyya M, Sarma MP, Bhattacharjee M, Basak M, Kashyap MP, Bhattacharjee S, Ali E, Keppen C, Kalita S, Kalita MJ, Das PP, Hazarika G, Deka AJ, Dutta K, Idris MG, Akhtar S, Medhi S. Expression of Interleukin-8, Interleukin-12 and Interleukin-13 in Esophageal Squamous Cell Carcinoma: Biomarker Potentiality and Prognostic Significance. J Gastrointest Cancer. 2024 Sep; 55(3):1239-1255. doi: 10.1007/s12029-024-01063-1. Epub 2024 Jun 23. PMID: 38910194.
  8. Paul A, Sarma V, Choudhury P, Pegu G, Sarma K, Sarma A, Saikia L. Scrub typhus- An underestimated infectious disease attributable to community acquired Acute Kidney Injury. Indian Journal of Microbiology. 64(1):133-140, 2024. DOI:10.1007/s12088-023-01137-x.
  9. Sarmah K, Sarma K, Borkakoty B, Borah PK, Sharma A, Mahanta J. Molecular characterization of Mumps virus genotype C detected from Dibrugarh district of Assam, India. Indian J Med Res. 2024 Jun;159(6):663-670. doi: 10.25259/IJMR_2312_23. PMID: 39382474; PMCID: PMC11463867.
  10. Saha P, Hegde M, Chakraborty K, Singha A, Kunnumakkara A.B, Khan MS, Ahmad I, Ghosh A, Kumer A, Sil SK (2024). Targeted inhibition of colorectal cancer proliferation: The dual-modulatory role of 2,4-DTBP on anti-apoptotic Bcl-2 and Survivin proteins. Journal of Cellular and Molecular Medicine. (In press). IF: 5.3
  11. Das, P., Majumder, R., Sen, N., Nandi, S. K., Ghosh A, Mandal, M., & Basak, P. (2024). A computational analysis to evaluate deleterious SNPs of GSK3β, a multifunctional and regulatory protein, for metabolism, wound healing, and migratory processes. International Journal of Biological Macromolecules, 256, 128262. IF: 8.20
  12. Sarmah K, Sarma K, Borah PK, Mahanta J, Borkakoty B, Kaur H. (2023). Co-circulation of two Mumps virus genotypes in Assam, India. Virus Genes. 59(4):515-523. IF: 2.19
  13. Bharadwaj, K. K., Rabha, B., Ahmad, I., Mathew, S., Bhattacharjee, C. K., Jaganathan, B. G., Poddar, S., Patel, H., Subramaniyan, V., Chinni, S. V., Ramachawolran, G., Saleem, R. M., Ali, E., Abdel-Daim, M. M., Baishya, D., & Ghosh, A. (2023). Rhamnetin, a nutraceutical flavonoid arrests cell cycle progression of human ovarian cancer (SKOV3) cells by inhibiting the histone deacetylase 2 protein. Journal of Biomolecular Structure & Dynamics. IF: 4.8
  14. Agarwala, Pratibha; Ghosh, Arabinda; Hazarika, Priyanka; Acharjee, Debopam; Ghosh, Shirsendu; Rout, Debasish; Sasmal, Dibyendu (2023) Unraveling the Interaction of Diflunisal with Cyclodextrin and Lysozyme by Fluorescence Spectroscopy. The Journal of Physical Chemistry Part B. 127, 45, 9710-9723. IF: 3.25
  15. Kumar, R. R., Jain, R., Akhtar, S., Parveen, N., Ghosh Arabinda, Sharma, V., & Singh, S. (2023). Characterization of thiamine pyrophosphokinase of vitamin B1 biosynthetic pathway as a drug target of Leishmania donovani. Journal of Biomolecular Structure & Dynamics, 1-17. IF: 4.8
  16. Mukerjee, N., Maitra, S., Ghosh Arabinda, Subramaniyan, V., & Sharma, R. (2023). Exosome‐mediated PROTACs delivery to target viral infections. Drug Development Research. IF: 3.8
  17. Mukerjee, N., & Ghosh Arabinda. (2023). Revolutionizing viral disease treatment: PROTACs therapy could be the ultimate weapon of the future. Journal of Medical Virology, 95(8). IF: 12.7
  18. Mukerjee, N., Rohit Sarma & Ghosh Arabinda (2023) Revolutionizing Viral Disease Treatment: PROTACs Therapy Could be the Ultimate Weapon of the Future. Journal of Medical Virology. 95(8):e28981. IF: 12.7
  19. Gurnani, M., Chauhan, A., Ranjan, A., Gopi, P., Ghosh Arabinda, Tuli, H. S., Haque, S., Pandya, P., Lal, R., & Jindal, T. (2023). Cyanobacterial compound Tolyporphine K as an inhibitor of Apo-PBP (penicillin-binding protein) in A. baumannii and its ADME assessment. Journal of Biomolecular Structure & Dynamics, 1-12. IF: 4.8
  20. Pinky Rani Biswas, Pinaki Chattopadhyay, Sudeshna Nandi, Arabinda Ghosh, Krishnendu Acharya and Arun Kumar Dutta (2023) Investigation of antioxidant activity, myco-chemical content, and GC-MS based molecular docking analysis of bioactive chemicals from Amanita konajensis, a tribal myco-food from India. International Journal of Medicinal Mushrooms. 26(1):27-44. IF: 1.3
  21. Alqahtani, T., Deore, S. L., Kide, A. A., Shende, B. A., Sharma, R. K., Chakole, R. D., Nemade, L. S., Kale, N., Borah, S., Deokar, S. S., Behera, A., Bhandari, D. D., Gaikwad, N., Ferdosh, S., & Ghosh Arabinda. (2023). Mitochondrial dysfunction and oxidative stress in Alzheimer’s disease, and Parkinson’s disease, Huntington’s disease and Amyotrophic Lateral Sclerosis -An updated review. Mitochondrion, 71, 83-92. IF: 4.4
  22. S. Fegade, Shailaja. B. Jadhav, Somadatta Y. Chaudhari, Deepak T. Tandale, Shams Tabrez, Mohd Shahnawaz Khan, Syed Kashif Zaidi, Arabinda Ghosh (2023). Synthesis and Computational Insights of flavone derivatives as Potential Estrogen Receptor Alpha (ER-α) antagonist. Journal of Biomolecular Structure & Dynamics. 1-10. IF: 4.8
  23. Kanak Chakraborty, Partha Saha, Arabinda Ghosh, and Samir K. Sil (2023) Exploration of Rhinacanthone, a Natural Naphthoquinone, as a Potential Human Papilloma Virus E7 Oncoprotein Inhibitor (HPV-E7i) Through AI-Based Protein Modeling, Molecular Docking, and Simulation Studies. Proceedings of the NIELIT’s International Conference on Communication, Electronics and Digital Technology (Springer Nature). 676:577-591.
  24. Mukerjee, N., Maitra, S., Arabinda Ghosh, & Sharma, R. (2023). Impact of CAR-T cell therapy on treating viral infections: unlocking the door to recovery. Human Cell, 36(5), 1839-1842. IF: 4.374.

Research Scholars

Research Scholars

Name of Scholars

  1. Titikhya Baruah
  2. Preetam Shree Pathak
  3. Kabyashree Borah
  4. Kamalakshi Chowdhury

Achievement

  1. Titikhya Baruah cleared CSIR NET Life Science, Dec 2024, Assistant Professor (All Indian Rank: 36)

Activities

  • Organized 3-Days National Workshop on “Emerging trends in Artificial Intelligence and Machine Learning  in Biomedical Application”, 19 - 25 February 2025

Department Contact Info

DEPARTMENT Of COMPUTATIONAL BIOLOGY & BIOTECHNOLOGY

MSSV Guwahati Unit, Rupnagar, Guwahati-32, Assam

Mon – Fri 9:00A.M. – 5:00P.M.

Social Info

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