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Admission 2024-25

Dr. Kishore Sarma

kishore.sarma07@gmail.com
8471891554
Computational Biology & Biotechnology
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Dr. Kishore Sarma

HoD(i/c) & Assistant Professor
Education - M.Sc. (Tech) Bioinformatics, DOEACC Bioinformatics “B” Level, Ph.D.
Area of Interest - Computational Genomics & Proteomics
Research
Academic/Administrative Responsibilities
Awards
Workshop Attended/ Conducted
Other Informations

Published Books:

  1. Computational Biology and Biostatistics: As per CBCS Syllabus. Kishore Sarma, Manas Das, Aashis Dutta. Kalyani Publishers. (ISBN 978-93-5540-543-2)
  2. An Approach to Microbial Biotechnology: A Laboratory Handbook: Sudipta Sankar Bora, Kishore Sarma, Saurav Das. LAP LAMBERT Academic Publishing (ISBN 978-3-659-40108-4).
  3. Modern Approach to Microbiology and Allied Biosciences: Sudipta Sankar Bora, Kishore Sarma, Ratul Nath, Saurav Das, Jyoti Prasad Lahan, Rituparna Kalita, Archana Deka, Madhusmita Borah, Samanwita Goswami and Gunajit Goswami. Published by Kaustubh Prakashan (ISBN 978-93-82283-34-8).

 

Published Book Chapter:

  1. Parida P, Sarma K, Borkakoty B, Mohapatra PK: Structure and Functional Differentiation of PfCRT Mutation in Chloroquine Resistance (CQR) in Plasmodium falciparum Malaria. Current Topics in Malaria edited by Alfonso J. Rodriguez-Morales, ISBN 978-953-51-2790-1, Print ISBN 978-953-51-2789-5, InTech, November 11, 2016

 

Publications:

1.      Saikia Q, Adhikari K, Sanjeev A, Hazarika A, Sarma K. Isoliquiritigenin: a potential drug candidate for the management of erectile dysfunction. Journal of Pharmacy and Pharmacology. (Accepted for publication on 20th April 2024)

2.      Das S, Medhi D, Talukdar AJ, Raja D, Sarma K, Sarma A, Saikia L. Hepatitis C Virus genotypes among population with reported risk factors in Assam, Northeast India: Emergence of Genotype-8. Indian Journal of Medical Research. (Accepted for publication)

3.      Paul A, Sarma V, Choudhury P, Pegu G, Sarma K, Sarma A, Saikia L. Scrub typhus- An underestimated infectious disease attributable to community acquired Acute Kidney Injury. Indian Journal of Microbiology. 64(1):133-140, 2024

4.      Baro M, Das M, Kalita A, Das B, Sarma K. Exploring the anti-inflammatory potential of Colocasia esculenta root extract in in-vitro and in-vivo models of inflammation. Journal of Ethnopharmacology. 303:116021, 2023

5.      Sarmah K, Sarma K, Borah PK, Mahanta J, Borkakoty B, Kaur H. Co-circulation of two Mumps virus genotypes in Assam, India. Virus Genes. 59(4):515-523, 2023

6.      Sarma K, Bali NK, Sarmah N, Borkakoty B. In silico screening of prospective MHC class I and II restricted T-cell based epitopes of the spike protein of SARS-CoV-2 for designing of a peptide vaccine for COVID-19. COVID. 2: 1731-1747, 2022

7.      Chutia P, Das M, Goswami N, Choudhury M, Saha N, Sarma K. Deciphering the role of aquaporin 1 in the adaptation of the stinging catfish Heteropneustes fossilis to environmental hypertonicity by molecular dynamics simulation studies. Journal of bimolecular structure and dynamics. 18: 1-15, 2022

8.      Sajeed R, Sarma K, Sarmah K, Biswas D, Borkakoty B. Computational screening of potential MHC class I restricted cytotoxic T lymphocytes-based common multi-epitopes of major arboviral diseases. Future Virology. 15(8), 2020

9.      Patgiri SJ, Sarma K, Sarmah N, Bhattacharyya N, Sarma DK, Nirmolia T, Bhattacharyya DR, Mohapatra PK, Bansal D, Bharti PK, Sehgal R, Mahanta J, Sultan AA. Characterization of drug resistance and genetic diversity of Plasmodium falciparum parasites from Tripura, Northeast India. Scientific Report. 9(1):13704, 2019

10.  Biswas D, Dutta M, Sarmah K, Yadav K, Buragohain M, Sarma K, Borkakoty B. Genetic characterization of influenza A(H1N1) pdm09 viruses circulating in Assam, Northeast India during 2009 to 2015. Indian Journal of Medical Microbiology. 37(1):42-49, 2019

11.  Sarmah K, Borkakoty B, Sarma K, Hazarika R, Das PK, Jakharia A, Das M, Biswas D. Genetic variations of the Hemagglutinin gene of Pandemic Influenza A (H1N1) viruses in Assam, India during 2016. 3 Biotech. 8(10):408, 2018

12.  Borkakoty B, Das M, Sarma K, Jakharia A, Das PK, Bhattacharya C, Apum B, Biswas D. Molecular characterisation and phylogenetic analysis of dengue outbreak in Pasighat, Arunachal Pradesh, Northeast India. Indian Journal of Medical Microbiology. 36(1):37-42, 2018

13.  Sarma K, Roychoudhury S, Bora SS, Dehury B, Parida P, Das S, Das R, Dohutia C, Nath S, Deb B, Modi MK. Molecular modeling and dynamics simulation analysis of KATNAL1 for identification of novel inhibitor of sperm maturation. Combinatorial Chemistry & High Throughput Screening. 20(1):82-92, 2017

14.  Sarmah NP, Sarma K, Bhattacharyya DR, Bansal D, Sultan AH, Bharti PK, Singh N, Kaul H, Sehgal R, Mahanta J, Mohapatra PK. Molecular characterization of Plasmodium falciparum in Arunachal Pradesh from Northeast India based on Merozoite surface protein 1 (MSP1) and Glutamate Rich Protein (GLURP). Indian Journal of Medical Research. 146(3):375-380, 2017

15.  Sarmah NP, Sarma K, Bhattacharyya DR, Sultan AA, Bansal D, Singh N, Bharti PK, Sehgal R, Mohapatra PK, Parida P, Mahanta J. Antifolate drug resistance: Novel mutations and haplotype distribution in dhps and dhfr from Northeast India. Journal of Biosciences. 42(4):531-535, 2017

16.  Dohutia C, Chetia D, Gogoi K, Bhattacharyya DR, Sarma K. Molecular docking, synthesis and in vitro antimalarial evaluation of certain novel curcumin analogues. Brazilian Journal of Pharmaceutical Sciences. 53(4):e00084, 2017

17.  Dohutia C, Chetia D, Gogoi K, Sarma K. Design, in silico and in vitro evaluation of curcumin analogues against Plasmodium falciparum. Experimental Parasitology. 2017 175: 51-58, 2017

18.  Bora SS, Keot J, Das S, Sarma K, Barooah M. Metagenomics analysis of microbial communities associated with a traditional rice wine starter culture (Xaj-pitha) of Assam, India. 3 Biotech. 6(2): 153, 2016

19.  Bora SS, Sarma K, Das S, Barooah M. Structural and Functional analysis of Glutamate Decarboxylase System in Bacillus aryabhattai. Research journal of biotechnology. 11, 2016

20.  Sarma K, Borkakoty BJ, Parida P, Jakharia A, Dey D, Biswas D, Panda D, Modi M, Mohapatra PK, Jagadish Mahanta: In silico Identification of natural lead molecules from the genus of Phyllanthus against Hepatitis B Virus Reverse Transcriptase. The Natural Products Journal. 6: 292­304, 2016          

21.  Sarma K, Bora SS, Jakharia A, Mohapatra PK, Borkakoty B. Immunoinformatics screening of prospective MHC Class I restricted cytotoxic T-cell based epitopes in Zika virus. International Journal of Current Advanced Research. 5(9): 1229-1235, 2016.

22.  Sarma K, Borkakoty BJ, Parida P, Bora SS, Mohapatra PK, Biswas D, Mahanta J: Identification of natural lead molecules of Centella asiatica and Azadirachta indica targeting cholera toxin through structure based drug design. Indo Amrican Journal of Pharmaceutical Research. 6, 6418-6429, 2016.

23.  Sarma K, Roychoudhury S, Sarmah K, Bora SS, Choudhury MD, Modi MK. In silico Approaches Provide New Insights into the Structural and Functional Organization of Different Plant AGPases. Advances in Life Sciences. 5(12): 4978-4985, 2016

24.  Sarma K, Sen P, Barooah M, Choudhury, MD, Roychoudhury S, Modi MK. Structural comparison, substrate specificity and inhibitor binding of AGPase small subunit from monocot and dicot: Present insight and future potential. Biomed Research International. 2014:583606, 2014

25.  Borkakoty B, Sarma K, Parida P, Prakash A, Mohapatra PK, Mahanta J. In silico screening of antifolate based novel inhibitors from Brucea mollis Wall. ex kurz against quadruple mutant drug resistant PfDHFR. Combinatorial Chemistry & High Throughput Screening. 17(8): 681-93, 2014

26.  Parida P, Yadav RNS, Sarma K: Insight into Structural Organization and Protein-Protein Interaction of Non-Structural 3 (NS3) Proteins from Dengue Serotypes. Current Pharmaceutical Biotechnology. 15: 156-172, 2014.

27.  Parida P, Yadav RN, Sarma K, Nainwal LM. Design, Virtual Screening and Docking Study of Novel NS3 Inhibitors by Targeting Protein-protein Interacting Sites of Dengue Virus - A Novel Approach. Current Pharmaceutical Biotechnology. 14(11): 995-1008, 2014

28.  Das R, Gogoi D, Bhoumick S, Saikia S, Bezbaruah RL, Bora TC, Sarma K, Sahu M, Barooah M. 3D- Comparative Modelling, Structure Comparison & Docking Studies for AVPR2 Protein with Some Anti-Diabetic Plant Compounds from North East India. Indo Global Journal of Pharmaceutical Sciences. 4(1): 8-17, 2014

29.  Dehury B, Sahu M, Sahu J, Sarma K, Sen P, Modi MK, Barooah M, Choudhury MD. Structural analysis and molecular dynamics simulations of novel δ-endotoxin Cry1Id from Bacillus thuringiensis to pave the way for development of novel fusion proteins against insect pests of crops. Journal of Molecular Modeling. 19(12): 5301-16. 2013

30.  Dehury B, Sahu M, Patra MC, Sarma K, Sahu J, Sen P, Modi MK, Choudhury MD, Barooah M. Insights into the structure-function relationship of disease resistance protein HCTR in maize (Zea mays L.): a computational structural biology approach. Journal of Molecular Graphics & Modeling. 45: 50-64, 2013

31.  Dehury B, Sahu M, Sarma K, Sahu J, Sen P, Modi MK, Sharma GD, Choudhury MD, Barooah M. Molecular phylogeny, homology modeling, and molecular dynamics simulation of race-specific bacterial blight disease resistance protein (xa5) of rice: a comparative agriproteomics approach. OMICS- A Journal of Integrative Biology. 17(8): 423-38. 2013

32.  Dehury B, Panda D, Sahu J, Sahu M, Sarma K, Barooah M, Sen P, Modi M. In silico identification and characterization of conserved miRNAs and their target genes in sweet potato (Ipomoea batatas L.) Expressed Sequence Tags (ESTs). Plant Signaling & Behavior. 8(12). pii: e26543, 2013

33.  Sahu M, Sahu J, Sarma K, Dehury B, Sen P, Modi M K and Barooah M. In silico 3-D modelling and characterization of actin1 of Arabidopsis thaliana. Biotechnologia. 94(4): 432-443, 2013

34.  Sarma K, Dehury B, Sahu J, Sarmah R, Sahoo S, Sahu M, Sen P, Modi MK, Barooah M. A comparative proteomic approach to analyse structure, function and evolution of rice chitinases: a step towards increasing plant fungal resistance. Journal of Molecular Modeling. 18(11):4761-80, 2012

35.  Swargiary A, Verma AK, Sarma K. Homology modeling and docking studies of phosphoenolpyruvate carboxykinase in Schistosoma mansoni. Medicinal Chemistry Research. 22(6): 2870-2878, 2012

36.  Dehury B, Sarma K, Sarmah R, Sahu J, Sahoo S, Sahu M, Sen P, Modi MK, Sharma GD, Choudhury MD, Barooah M. In silico analyses of superoxide dismutases (SODs) of rice (Oryza sativa L.). Journal of Plant Biochemistry and Biotechnology.  22(1): 150-156, 2012

37.  Sahu M, Sahu J, Sahoo S, Dehury B, Sarma K, Sarmah R, Sen P, Modi MK, Barooah M. An approach to delineate primers for a group of poorly conserved sequences incorporating the common motif region. Bioinformation. 8(4): 181-184, 2012

38.  Sahu J, Sarmah R, Dehury B, Sarma K, Sahoo S, Sahu M, Barooah M, Modi MK, Sen P. Mining for SSRs and FDMs from expressed sequence tags of Camellia sinensis. Bioinformation. 8(6): 260-266, 2012

39.  Sarmah R, Sahu J, Dehury B, Sarma K, Sahoo S, Sahu M, Barooah M, Sen P, Modi MK. ESMP: A high-throughput computational pipeline for mining SSR markers from ESTs. Bioinformation. 8(4): 206-8, 2012

 

Conferences:

1.   

Sarma K, Dehury B, Sahu J, Sahu M, Sen P, Barooah M, Modi MK and Roychoudhury S. (2012). “An In silico Analysis of Structure, Function and Evolution of Rainbow Smelt (Osmerusmordax) Type II Antifreeze Protein.” “WET LAND -2012”, Department of Life Science & Bioinformatics, Assam University, Silchar, Assam.

2.   

Sarma K, Dehury B, Sahu J, Sahu M, Sen P, Barooah M and Modi MK . (2012). “In silico structural comparison and substrate specificity of AGPase small subunit from monocot and dicot crop plants: present insight and future potential”, “Workshop-II: DBT-AAU Centre", Department of Agril. Biotechnology, AAU, Jorhat, Assam.

3.   

Sahu J, Sarmah R, Dehury B, Sarma K, Sahu M, Sahoo S, Barooah M, Modi MK and Sen P. (2012). “A comparative study of various statistical approaches used for in silico analysis of Quercetin Microarray data”, “ICABS – International Conference on Advances in Biological Sciences", Department of Biotechnology and Microbiology and Inter University Centre for Biosciences, Kannur University, Kerala.

4.   

Sahu J, Phukon M, Sarmah R, Dehury B, Sarma K, Sahu M, Barooah M, Modi MK and Sen P. (2012). “In silico study of the gene expression data for over expression of Os WRKY13, an activator of disease resistance in Rice”, DBT sponsored national seminar on “Prospects of Molecular Biological and Biotechnological Applications for Human Welfare”, Department of Biotechnology, Pandu College, Assam.

5.   

Sahu J, Sarmah R, Dehury B, Sarma K, Sahu M, Barooah M, Modi MK and Sen P. (2012). “In silico mining and phylogeny study of stress specific microRNAs from Genomic Survey Sequences of Oryza sativa L”, “Workshop-II: DBT-AAU Centre", Department of Agril. Biotechnology, AAU, Jorhat, Assam.

6.   

Sahu J, Sarmah R, Dehury B, Sarma K, Sahu M, Barooah M, Modi MK and Sen P. (2012). “Development and characterization of EST derived SSRs for Labeorohita using bioinformatics approaches.” “WET LAND -2012”, Department of Life Science & Bioinformatics, Assam University, Silchar, Assam.

7.   

Sahu M, Dehury B, Sahu J, Sarma K, Sen P, Modi MK and Barooah M. (2012). “Comparative characterization of Structural aspect imbibing Acid tolerance response of Glutathione Synthetase (GshB) in Mesorhizobium loti”, “Workshop-II: DBT-AAU Centre", Department of Agril. Biotechnology, AAU, Jorhat, Assam.

8.   

Sahu M, Dehury B, Sahu J, Sarma K, Sen P, Modi MK and Barooah M. (2012). “Comparative modeling and characterization of Growth Hormone Protein of Labeo rohita defining the Hormone-Receptor Interfaces”, “WET LAND -2012”, Department of Life Science & Bioinformatics, Assam University, Silchar, Assam.

Academic/Administrative Responsibilities

  • Head (i/c), Department of Computational Biology and Biotechnology
  • Member, Viksit Bharat Cell of MSSV for necessary compliance of the Viksit Bharat@2047 initiatives at MSSV
  • Member, Research & Development Cell of MSSV

 

Awards

  • ICMR Research Associateship (Post Doctoral Fellow) received on 12th March, 2021 for the project entitled “A computational system biology approach for risk assessment of environmental chemicals on human health”
  • Secured 1st prize in the Best Scientific Paper competition of RMRC Dibrugarh held on 18th July 2014 under category Poster.

 

National Seminar:

  1. Two days National Seminar on “Challenges and opportunities posed by Biotechnology and IPR” organized by PES College of Pharmacy. January 20th & 21st, 2006.

Workshop Attended/ Conducted

Workshops Attended:

1.

 

1. Participated in the Pre-Conference workshop entitled “Hands on WHONET Training” organized under 44th Annual Conference of Indian association of Medical Microbiologist held at Guwahati. 21st December, 2021.

2.       

2. Participated in the Two days “Hands on training on Bioinformatics” organized under Indo-UK project on Antimicrobial Resistance funded by DBT. 17th -18th February, 2020.

3.       

3. Participated in the Two days workshop on “Research Methodology & Paper Writing Techniques”, organized by the Department of Health Research, ICMR, New Delhi and ICMR-RMRC, NE Region Dibrugarh. 25th & 26th May, 2019.

4.       

4. Participated in the “Outreach Program” organized by ICMR- Regional Medical Research Centre, N.E. Region, Dibrugarh under the banner 4th INDIA INTERNATIONAL SCIENCE FESTIVAL-2018. 27th September, 2018.

5.       

5. Participated in the Two days workshop on “Research Methodology” organized by Regional Medical Research Centre, N.E. Region, Indian Council of Medical Research (ICMR), Dibrugarh - 786001, Assam in association with DHR Funded scheme “Viral Research and Diagnostic Laboratory”. 27th & 28th June, 2016. Acted as organizing member.

6.       

6. Participated in the Three Days Workshop on “Basic Techniques in Bioinformatics” Organized by Bioinformatics Facility, Department of Biotechnology, Indian Institute of Technology Guwahati. 12th -14th October, 2011

 

Workshop (Acted as Resource Person):

1.       

Hands on training program supported by DBT, GOI entitled “Fundamentals of Bioinformatics, Drug Discovery and Molecular Dynamics Simulation” organized by the Bioinformatics Centre, Department of Zoology, Gauhati University, Guwahati during 2nd - 9th January, 2024

2.       

One day workshop on Bioinformatics organized by the department of Zoology, J. N. College, Boko, Assam. November 1st, 2023.

3.       

Six days workshop on Computer aided drug designing and molecular docking” organized by the department of Zoology, Gauhati University, Guwahati, Assam. December 12th - 17th, 2022.

4.       

Delivered a talk on "Molecular Docking for Beginners" at Pratiksha Institute of Pharmaceutical Sciences on 7th May, 2022.

5.       

Six days workshop on “Hands on Training on Bioinformatics Tools and Techniques” organized by the Bioinformatics center, Gauhati University, Guwahati, Assam. October 25th - 30th, 2021.

6.       

Four days workshop on “Hands on Basic Bioinformatics and Sequence Analysis Training Using Bioinformatics Tools as a Faculty Development Programme” organized by the Bioinformatics center, Gauhati University, Guwahati, Assam. February 3rd - 6th, 2020

7.       

Two days workshop on “Applications of Bioinformatics Tools in Biomedical Research” Sponsored by the ICMR-Regional Medical Research Centre, N.E. Region, Dibrugarh. March 22nd & 23rd, 2018.

8.       

One day workshop on “DNA Sequence Analysis using Bioinformatics Tools” Organized by Regional Medical Research Centre, NE Region (ICMR), Dibrugarh. June 27th, 2017.

9.       

Two days workshop on “Bioinformatics: Current Approaches and Applications in Biomedical Research” Organized by the Biomedical Informatics Centre of ICMR, RMRC, Dibrugarh. March 28th & 29th, 2017.

10.   

One day workshop on “Application of Bioinformatics in Biomedical Research” Organized by the Biomedical Informatics Centre of ICMR, RMRC, Dibrugarh. March 28th, 2016.

11.   

Two Days Hands on workshop on “Sequencing and Post Sequencing Analysis” Organized by Assam Medical College and Hospital, Dibrugarh. March 21st & 22nd, 2016.

 

Symposium:

  1. One day symposium on “Viral Infections Trends & Updates” Organized by Regional Medical Research Centre, NE Region (ICMR), Dibrugarh. May 22nd
  2. One day Symposium on “RMRC - GATC One Day Symposium” an initiative from Bencos Scientific Society (A Non Profotable Organization) in Association with GENOMICS ANALYSIS AND TECHNOLOGY on July 5th, 2017.

CME:

  1. Two days CME on “Current Understanding of Immunology” organized by Regional Medical Research Centre, NE Region (ICMR), Dibrugarh-786001, Assam in Association with Indian Immunological Society and MRHRU. 26th & 27th May 2016.